Yes, you can mix and match different routes. The city where your first tour ends should also be the city where your second tour begins. Take note: you must arrange your own accomodation in this city.
For example,
You’d like to travel from Da Lat to Mekong Delta via Ho Chi Minh City (Saigon). This tour combines tours A ‘Da Lat to Ho Chi Minh in 4 days’ and B ‘Ho Chi Minh to Mekong Delta in 1 day.’ Accommodation in Ho Chi Minh City is not included when booking this combination.

